Tcf15 promotes an open nucleolar chromatin state to safeguard ribosome biogenesis and genome stability in mouse embryonic stem cells

• Yu-ping Dong,

  Roles Formal analysis, Investigation

  Affiliations State Key Laboratory of Genetic Evolution and Animal Models, Key Laboratory of Animal Models and Human Disease Mechanisms of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, University of Chinese Academy of Sciences, Beijing, China

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• Yi-Min Chen,

  Roles Formal analysis

  Affiliations University of Chinese Academy of Sciences, Beijing, China, Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Min Tang,

  Roles Methodology

  Affiliation State Key Laboratory of Genetic Evolution and Animal Models, Key Laboratory of Animal Models and Human Disease Mechanisms of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China

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• Hu Zhou ,

  Roles Data curation, Formal analysis

  * E-mail: zhouhu@simm.ac.cn (HZ), wanglin2015@mail.kiz.ac.cn (LW), zhengp@mail.kiz.ac.cn (PZ)

  Affiliation Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Lin Wang ,

  Roles Data curation, Formal analysis, Methodology, Visualization

  * E-mail: zhouhu@simm.ac.cn (HZ), wanglin2015@mail.kiz.ac.cn (LW), zhengp@mail.kiz.ac.cn (PZ)

  Affiliation State Key Laboratory of Genetic Evolution and Animal Models, Key Laboratory of Animal Models and Human Disease Mechanisms of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China

  https://orcid.org/0000-0003-3764-2157

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• Ping Zheng

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft

  * E-mail: zhouhu@simm.ac.cn (HZ), wanglin2015@mail.kiz.ac.cn (LW), zhengp@mail.kiz.ac.cn (PZ)

  Affiliations State Key Laboratory of Genetic Evolution and Animal Models, Key Laboratory of Animal Models and Human Disease Mechanisms of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China

  https://orcid.org/0000-0003-0402-5507

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