Heme acts as a metabolic brake on erebosis in the Drosophila gut

• Motohiro Morikawa,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Division of Developmental Biology and Regenerative Medicine, Kobe University, Kobe, Japan, Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

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• Tetsutaro Hayashi,

  Roles Investigation, Methodology

  Affiliation Omics AI Research Team, Advanced General Intelligence in Science Program (AGIS), TRIP Headquarters, RIKEN, Wako, Japan

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• Yuko Ikegawa,

  Roles Investigation, Methodology

  Affiliation Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

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• Tomomi Takano,

  Roles Investigation, Methodology

  Affiliation Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

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• Kazuya Wata,

  Roles Investigation, Methodology

  Affiliations Division of Developmental Biology and Regenerative Medicine, Kobe University, Kobe, Japan, Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

  ⨯
• Hirohisa Kyogoku,

  Roles Investigation, Methodology

  Affiliations Graduate School of Agricultural Science, Kobe University, Kobe, Japan, Laboratory for Chromosome Segregation, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

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• Mariko Kuse,

  Roles Investigation, Methodology

  Affiliation Omics AI Research Team, Advanced General Intelligence in Science Program (AGIS), TRIP Headquarters, RIKEN, Wako, Japan

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• Mika Yoshimura,

  Roles Investigation, Methodology

  Affiliation Omics AI Research Team, Advanced General Intelligence in Science Program (AGIS), TRIP Headquarters, RIKEN, Wako, Japan

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• Hiroshi Nishida,

  Roles Investigation, Methodology

  Affiliation Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

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• Rahul Parit,

  Roles Investigation, Methodology

  Affiliations Division of Developmental Biology and Regenerative Medicine, Kobe University, Kobe, Japan, Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

  ⨯
• Dao My Linh,

  Roles Investigation, Methodology

  Affiliations Division of Developmental Biology and Regenerative Medicine, Kobe University, Kobe, Japan, Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

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• Kanta Kawai,

  Roles Investigation, Methodology

  Affiliation Laboratory of Chemical Biology, Gifu Pharmaceutical University, Gifu, Japan

  ⨯
• Tasuku Hirayama,

  Roles Investigation, Methodology

  Affiliation Laboratory of Chemical Biology, Gifu Pharmaceutical University, Gifu, Japan

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• Chun Wang Sy,

  Roles Investigation

  Affiliation Faculty of Science, University of Hong Kong, Hong Kong, China

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• Kan Etoh,

  Roles Investigation, Methodology

  Affiliation Department of Molecular Cell Biology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

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• Itoshi Nikaido,

  Roles Funding acquisition, Investigation, Methodology, Project administration, Supervision

  Affiliations Omics AI Research Team, Advanced General Intelligence in Science Program (AGIS), TRIP Headquarters, RIKEN, Wako, Japan, Department of Functional Genome Informatics, Division of Biological Data Science, Medical Research Laboratory, Institute of Integrated Research (IIR), Institute of Science Tokyo, Tokyo, Japan

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•  [ ... ],
• Sa Kan Yoo

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sakan.yoo@riken.jp

  Affiliations Division of Developmental Biology and Regenerative Medicine, Kobe University, Kobe, Japan, Laboratory for Homeodynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan

  https://orcid.org/0000-0003-3358-4818

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