Competing value signals impair reward-learning via dopaminergic mechanisms and increase exploration

Wen-Wei Lin; Pei-Yu Lee; Hsin-Yun Tsai; Yi-Hsuan Lin; Min-Min Lin; Zheng-Liang Lu; Mei-Yu Yeh; Ming-Tsung Tseng

doi:10.1371/journal.pbio.3003922

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Open Access

Peer-reviewed

Research Article

Competing value signals impair reward-learning via dopaminergic mechanisms and increase exploration

Wen-Wei Lin,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan
⨯
Pei-Yu Lee,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources

Affiliation Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan
⨯
Hsin-Yun Tsai,

Roles Data curation, Methodology, Writing – review & editing

Affiliation Taiwan International Graduate Program in Interdisciplinary Neuroscience, National Taiwan University and Academia Sinica, Taipei, Taiwan
⨯
Yi-Hsuan Lin,

Roles Data curation, Writing – review & editing

Affiliation Taiwan International Graduate Program in Interdisciplinary Neuroscience, National Taiwan University and Academia Sinica, Taipei, Taiwan
⨯
Min-Min Lin,

Roles Data curation, Methodology, Writing – review & editing

Affiliation Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan
⨯
Zheng-Liang Lu,

Roles Methodology, Software

Affiliation Department of Computer Science and Information Engineering, National Taiwan University, Taipei, Taiwan
⨯
Mei-Yu Yeh,

Roles Data curation

Affiliation Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan
⨯
Ming-Tsung Tseng

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: mingtsungtseng@ntu.edu.tw

Affiliation Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan

https://orcid.org/0000-0003-3763-9548

⨯

Competing value signals impair reward-learning via dopaminergic mechanisms and increase exploration

Wen-Wei Lin,
Pei-Yu Lee,
Hsin-Yun Tsai,
Yi-Hsuan Lin,
Min-Min Lin,
Zheng-Liang Lu,
Mei-Yu Yeh,
Ming-Tsung Tseng

Published: July 24, 2026
https://doi.org/10.1371/journal.pbio.3003922

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