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Open Access
Peer-reviewed
Research Article
The microglia-derived protein Sema4ab attenuates regenerative neurogenesis after spinal cord injury in zebrafish
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Alberto Docampo-Seara ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: alberto.docampo_seara@tu-dresden.de
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Mehmet Ilyas Cosacak ,
Contributed equally to this work with: Mehmet Ilyas Cosacak, Kim Heilemann
Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Kim Heilemann ,
Contributed equally to this work with: Mehmet Ilyas Cosacak, Kim Heilemann
Roles Formal analysis, Investigation, Methodology, Validation, Visualization
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Friederike Kessel,
Roles Methodology, Software
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Ana-Maria Oprişoreanu,
Roles Investigation
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Markus Westphal,
Roles Investigation
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Özge Çark,
Roles Investigation
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Daniela Zöller,
Roles Investigation
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Josi Arnold,
Roles Investigation
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Anja Bretschneider,
Roles Formal analysis, Investigation
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Alisa Hnatiuk,
Roles Resources
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Nikolay Ninov,
Roles Resources
Affiliation Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany
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Catherina G. Becker ,
Roles Conceptualization, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing
¶‡ CGB and TB also contributed equally to this work.
Affiliations Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany, Institute for Neuroscience and Cardiovascular Research, Chancellor’s Building, University of Edinburgh, Edinburgh, United Kingdom, Cluster of Excellence Physics of Life, TU Dresden, Dresden, Germany
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Thomas Becker
Roles Conceptualization, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing
¶‡ CGB and TB also contributed equally to this work.
Affiliations Center for Regenerative Therapies Dresden at the TU Dresden, Dresden, Germany, Institute for Neuroscience and Cardiovascular Research, Chancellor’s Building, University of Edinburgh, Edinburgh, United Kingdom
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The microglia-derived protein Sema4ab attenuates regenerative neurogenesis after spinal cord injury in zebrafish
- Alberto Docampo-Seara,
- Mehmet Ilyas Cosacak,
- Kim Heilemann,
- Friederike Kessel,
- Ana-Maria Oprişoreanu,
- Markus Westphal,
- Özge Çark,
- Daniela Zöller,
- Josi Arnold,
- Anja Bretschneider
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- Published: June 18, 2026
- https://doi.org/10.1371/journal.pbio.3003865