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Open Access
Peer-reviewed
Short Reports
Short Reports offer exciting novel biological findings that may trigger new research directions.
Growth arrest of Mycobacterium tuberculosis in acidic environments enhances their survival of antibiotic treatment
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Eun Seon Chung ,
Contributed equally to this work with: Eun Seon Chung, William C. Johnson
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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William C. Johnson ,
Contributed equally to this work with: Eun Seon Chung, William C. Johnson
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Tufts University Graduate School of Biomedical Sciences, Boston, Massachusetts, United States of America
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Maliwan Kamkaew,
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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Timothy A. Fitzgerald,
Roles Investigation, Writing – review & editing
Affiliations Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Tufts University Graduate School of Biomedical Sciences, Boston, Massachusetts, United States of America
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Morgan E. McNellis,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Tufts University Graduate School of Biomedical Sciences, Boston, Massachusetts, United States of America
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Trever C. Smith II,
Roles Methodology, Writing – review & editing
Affiliation Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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Srinivasan Vijay,
Roles Resources, Writing – review & editing
Affiliations Department of Microbial Pathogenesis and Immunology, Texas A & M University School of Medicine, Bryan, Texas, United States of America, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Nguyen Thuy Thuong Thuong,
Roles Resources, Writing – review & editing
Affiliations Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Shumin Tan,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Stuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Tufts University, Boston, Massachusetts, United States of America
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Bree B. Aldridge
Roles Conceptualization, Writing – original draft, Writing – review & editing
* E-mail: bree.aldridge@tufts.edu
Affiliations Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Stuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Tufts University, Boston, Massachusetts, United States of America, Department of Biomedical Engineering, Tufts University School of Engineering, Medford, Massachusetts, United States of America
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Growth arrest of Mycobacterium tuberculosis in acidic environments enhances their survival of antibiotic treatment
- Eun Seon Chung,
- William C. Johnson,
- Maliwan Kamkaew,
- Timothy A. Fitzgerald,
- Morgan E. McNellis,
- Trever C. Smith II,
- Srinivasan Vijay,
- Nguyen Thuy Thuong Thuong,
- Shumin Tan,
- Bree B. Aldridge
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- Published: June 22, 2026
- https://doi.org/10.1371/journal.pbio.3003857