Positive early-life olfactory memory is rooted in the olfactory bulb and triggers large-scale changes beyond the olfactory system

Jules Dejou; Anna Athanassi; Théo Brunel; Marc Thevenet; Anne Didier; Nathalie Mandairon

doi:10.1371/journal.pbio.3003845

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Peer-reviewed

Research Article

Positive early-life olfactory memory is rooted in the olfactory bulb and triggers large-scale changes beyond the olfactory system

Jules Dejou,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Lyon Neuroscience Research Center, Neuroplasticity and Neuropathology of Olfactory Perception Team, CNRS, UMR 5292, INSERM, U1028, University of Lyon, Lyon, France
⨯
Anna Athanassi,

Roles Investigation

Affiliation Lyon Neuroscience Research Center, Neuroplasticity and Neuropathology of Olfactory Perception Team, CNRS, UMR 5292, INSERM, U1028, University of Lyon, Lyon, France
⨯
Théo Brunel,

Roles Investigation

Affiliation Lyon Neuroscience Research Center, Neuroplasticity and Neuropathology of Olfactory Perception Team, CNRS, UMR 5292, INSERM, U1028, University of Lyon, Lyon, France
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Marc Thevenet,

Roles Software

Affiliation Lyon Neuroscience Research Center, Neuroplasticity and Neuropathology of Olfactory Perception Team, CNRS, UMR 5292, INSERM, U1028, University of Lyon, Lyon, France
⨯
Anne Didier ,

Contributed equally to this work with: Anne Didier, Nathalie Mandairon

Roles Conceptualization, Funding acquisition, Supervision, Visualization, Writing – review & editing

Affiliations Lyon Neuroscience Research Center, Neuroplasticity and Neuropathology of Olfactory Perception Team, CNRS, UMR 5292, INSERM, U1028, University of Lyon, Lyon, France, Institut Universitaire de France, Paris, France
⨯
Nathalie Mandairon

Contributed equally to this work with: Anne Didier, Nathalie Mandairon

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: nathalie.mandairon@cnrs.fr

Affiliation Lyon Neuroscience Research Center, Neuroplasticity and Neuropathology of Olfactory Perception Team, CNRS, UMR 5292, INSERM, U1028, University of Lyon, Lyon, France

https://orcid.org/0000-0001-7935-5215

⨯

Positive early-life olfactory memory is rooted in the olfactory bulb and triggers large-scale changes beyond the olfactory system

Jules Dejou,
Anna Athanassi,
Théo Brunel,
Marc Thevenet,
Anne Didier,
Nathalie Mandairon

Published: July 14, 2026
https://doi.org/10.1371/journal.pbio.3003845

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