Type II tRNA cleavage by SLFN14 endoribonuclease variants linked to inherited thrombocytopenia drives global translational repression

• Chengchao Ding,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Microbiology, Immunology‌‌ and Molecular Genetics, Joe R. & Teresa Lozano Long School of Medicine, The University of Texas at San Antonio, San Antonio, Texas, New York, United States of America, Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

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• Xinyi Ashley Liu,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Division of Nutritional Sciences, Cornell University, Texas, New York, United States of America

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• Fushun Zhang,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Microbiology, Immunology‌‌ and Molecular Genetics, Joe R. & Teresa Lozano Long School of Medicine, The University of Texas at San Antonio, San Antonio, Texas, New York, United States of America

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• Saori Uematsu,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Division of Nutritional Sciences, Cornell University, Texas, New York, United States of America

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• Shu-Bing Qian,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation Division of Nutritional Sciences, Cornell University, Texas, New York, United States of America

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• Yan Xiang

  Roles Conceptualization, Data curation, Formal analysis, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  ^* xiangy@uthscsa.edu

  Affiliation Department of Microbiology, Immunology‌‌ and Molecular Genetics, Joe R. & Teresa Lozano Long School of Medicine, The University of Texas at San Antonio, San Antonio, Texas, New York, United States of America

  https://orcid.org/0000-0002-7633-1629

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