USP39 promotes antiviral defense through post-transcriptional control of RIG-I and stabilization of STING

• Jiazheng Quan ,

  Contributed equally to this work with: Jiazheng Quan, Xibao Zhao

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China, Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China

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• Xibao Zhao ,

  Contributed equally to this work with: Jiazheng Quan, Xibao Zhao

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Shaoying Chen,

  Roles Investigation, Methodology

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Hongrui Li,

  Roles Methodology, Resources

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China

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• Wei Chen,

  Roles Formal analysis, Investigation

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Qianqian Di,

  Roles Investigation, Resources

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Xunwei Li,

  Roles Investigation, Validation

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Jiajing Zhao,

  Roles Investigation, Validation

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Han Wu,

  Roles Formal analysis, Validation

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Jin Chen,

  Roles Validation

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Yue Xiao,

  Roles Funding acquisition, Investigation, Methodology

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Zherui Wu,

  Roles Resources

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

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• Weilin Chen

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: cwl@szu.edu.cn

  Affiliation Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

  https://orcid.org/0000-0002-0335-4483

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