Altered salience network structure–function integration underlies the decline in cognitive flexibility during aging

• Xing Qian,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Wan Lin Yue,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore, Singapore

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• Kwun Kei Ng,

  Roles Data curation, Methodology, Project administration, Writing – review & editing

  Affiliation Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Ruth L. F. Leong,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Fang Ji,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Narayanaswamy Venketasubramanian,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Raffles Neuroscience Centre, Raffles Hospital, Singapore, Singapore

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• Saima Hilal,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Memory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Christopher Chen,

  Roles Data curation, Methodology, Project administration, Writing – review & editing

  Affiliation Memory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Michael W. L. Chee,

  Roles Conceptualization, Data curation, Project administration, Writing – review & editing

  Affiliation Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Dani S. Bassett,

  Roles Conceptualization, Methodology, Software, Writing – review & editing

  Affiliation Departments of Physics & Astronomy, Bioengineering, Electrical & Systems Engineering, Neurology, and Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Juan Helen Zhou

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: helen.zhou@nus.edu.sg

  Affiliations Centre for Sleep and Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore, Singapore, Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore, Department of Medicine, Healthy Longevity & Human Potential TRP, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

  https://orcid.org/0000-0002-0180-8648

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