Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci

• Guillaume Cerckel,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium

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• Denis Dereinne,

  Roles Data curation, Investigation

  Affiliation Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium

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• Laura Ledesma-García,

  Roles Investigation, Methodology

  Affiliation Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium

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• Vincent Meuric,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Nutrition Metabolisms and Cancer, INSERM, INRAE, Université de Rennes 1, CHU. de Rennes, Rennes, France

  https://orcid.org/0000-0001-5411-4001

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• Benoît Desguin,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium

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• Johann Mignolet,

  Roles Conceptualization, Formal analysis, Supervision, Validation, Writing – review & editing

  Affiliations Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium, Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland

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• Patrice Soumillion,

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium

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• Pascal Hols

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: Pascal.Hols@uclouvain.be

  Affiliation Louvain Institute of Biomolecular Science and Technology, Biochemistry and Genetics of Microorganisms, Université catholique de Louvain, Louvain-La-Neuve, Belgium

  https://orcid.org/0000-0001-8749-3650

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