Systematic identification of Salmonella T6SS effectors uncovers diverse new families and lipid-targeting activities

• Gianlucca G. Nicastro ,

  Contributed equally to this work with: Gianlucca G. Nicastro, Stephanie Sibinelli-Sousa

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing, Conceptualization

  Affiliations Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil, Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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• Stephanie Sibinelli-Sousa ,

  Contributed equally to this work with: Gianlucca G. Nicastro, Stephanie Sibinelli-Sousa

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliations Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil, Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, United States of America

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• Julia T. Hespanhol,

  Roles Data curation, Formal analysis, Visualization

  Affiliation Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, United States of America

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• Thomas W. C. Santos,

  Roles Data curation, Formal analysis

  Affiliation Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil

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• Joseph P. Munoz,

  Roles Formal analysis, Investigation, Methodology, Visualization

  Affiliation Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, United States of America

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• Rosangela S. Santos,

  Roles Formal analysis, Investigation, Methodology, Data curation

  Affiliation Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil

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• Blanca M. Perez-Sepulveda,

  Roles Resources

  Affiliation Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom

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• Sayuri Miyamoto,

  Roles Funding acquisition, Methodology, Supervision, Data curation

  Affiliation Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil

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• L. Aravind,

  Roles Data curation, Funding acquisition, Resources, Supervision

  Affiliation Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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• Robson F. de Souza ,

  Roles Investigation, Methodology, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing, Data curation, Formal analysis, Funding acquisition, Conceptualization

  * E-mail: rfsouza@usp.br (RFdS); ebayersantos@austin.utexas.edu (EB-S)

  Affiliation Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil

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• Ethel Bayer-Santos

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rfsouza@usp.br (RFdS); ebayersantos@austin.utexas.edu (EB-S)

  Affiliations Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil, Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, United States of America, LaMontagne Center for Infectious Disease, The University of Texas at Austin, Austin, Texas, United States of America

  https://orcid.org/0000-0003-3832-3449

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