Microglia sense fungal infections through capsular components from capillary-bound Cryptococcus neoformans via endothelial nucleotide signaling

• Chenxu Feng ,

  Contributed equally to this work with: Chenxu Feng, Ge Wang, Yixuan Wang

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Ge Wang ,

  Contributed equally to this work with: Chenxu Feng, Ge Wang, Yixuan Wang

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliations Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China

  ⨯
• Yixuan Wang ,

  Contributed equally to this work with: Chenxu Feng, Ge Wang, Yixuan Wang

  Roles Investigation, Methodology, Visualization

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Xiang Gao,

  Roles Investigation

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Zhenqi Xu,

  Roles Investigation

  Affiliations Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China

  ⨯
• Luyao Fang,

  Roles Investigation

  Affiliation Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China

  ⨯
• Ziyi Ma,

  Roles Formal analysis

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Suwei Zheng,

  Roles Investigation

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Yuyan Xie,

  Roles Resources

  Affiliation State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Yufeng Chu,

  Roles Investigation

  Current Address: Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Mei Meng,

  Roles Investigation

  Current Address: Department of Critical Care Medicine, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

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• Angela Yang,

  Roles Writing – review & editing

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Miriam Lu,

  Roles Writing – review & editing

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Judd Denzel Garcia Mondina,

  Roles Writing – review & editing

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Weiwei Zhu,

  Roles Investigation

  Affiliation Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Lisheng Zhang,

  Roles Funding acquisition, Investigation

  Affiliation Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China

  ⨯
• Linqi Wang,

  Roles Resources

  Affiliation State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Zongyan Chen ,

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  * E-mail: zychen@shvri.ac.cn (ZC); dongleisun@sjtu.edu.cn (DS)

  Affiliation Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China

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•  [ ... ],
• Donglei Sun

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – original draft

  * E-mail: zychen@shvri.ac.cn (ZC); dongleisun@sjtu.edu.cn (DS)

  Affiliations Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China, Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, Shanghai, China

  https://orcid.org/0000-0001-8222-3328

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