Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds

• Emoke Bakos ,

  Contributed equally to this work with: Emoke Bakos, Ádám Tiszlavicz

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliations Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary

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• Ádám Tiszlavicz ,

  Contributed equally to this work with: Emoke Bakos, Ádám Tiszlavicz

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary

  ⨯
• Viktor Szegedi,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Supervision, Validation, Visualization

  Affiliations Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary

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• Abdennour Douida,

  Roles Formal analysis, Investigation, Resources, Validation, Visualization

  Affiliation Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary

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• Szabina Furdan,

  Roles Formal analysis, Investigation

  Affiliation Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary

  https://orcid.org/0000-0002-8878-0966

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• Daphne K. Welter,

  Roles Data curation, Formal analysis, Methodology

  Affiliation European Molecular Biology Laboratory, Heidelberg, Germany

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• Jonathan M. Landry,

  Roles Data curation, Formal analysis

  Affiliation European Molecular Biology Laboratory, Heidelberg, Germany

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• Balazs Bende,

  Roles Methodology, Project administration

  Affiliation Hungarian Centre of Excellence for Molecular Medicine Research Group for Translational Medicine Development, Szeged, Hungary

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• Gabor Hutoczki,

  Roles Methodology, Resources

  Affiliation Department of Neurosurgery, University of Debrecen Clinical Centre, Debrecen Hungary

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• Pal Barzo,

  Roles Methodology, Resources

  Affiliation Department of Neurosurgery, University of Szeged, Szeged, Hungary

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• Gabor Tamas,

  Roles Resources

  Affiliation ELKH-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary

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• Vladimir Benes,

  Roles Data curation, Methodology, Validation

  Affiliation European Molecular Biology Laboratory, Heidelberg, Germany

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• Attila Szucs,

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation

  Affiliation Neuronal Cell Biology Research Group, Eötvös Loránd University, Budapest, Hungary

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• Karri Lamsa

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: klamsa@bio.u-szeged.hu, karri.lamsa@hcemm.eu

  Affiliations Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary

  https://orcid.org/0000-0002-4609-1337

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