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Open Access
Peer-reviewed
Research Article
The core outer junction protein CFAP77 connects A- and B-tubules within doublet microtubules of cilia and flagella
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Lan Xia ,
Contributed equally to this work with: Lan Xia, Guo-Liang Yin
Roles Data curation, Methodology
Affiliation Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, China
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Guo-Liang Yin ,
Contributed equally to this work with: Lan Xia, Guo-Liang Yin
Roles Data curation, Methodology
Affiliations Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, School of Life Sciences, University of Chinese Academy of Sciences, Beijing, China
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Yu Long,
Roles Data curation, Methodology
Affiliation Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, China
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Fei Sun,
Roles Funding acquisition, Writing – review & editing
Affiliations Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, School of Life Sciences, University of Chinese Academy of Sciences, Beijing, China, Center for Biological Imaging, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, China
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Bin-Bin Wang ,
Roles Funding acquisition, Supervision, Writing – review & editing
* E-mail: wbbahu@163.com (BW); zhuyun@ibp.ac.cn (YZ); chensr@bnu.edu.cn (SC)
Affiliations Center for Genetics, National Research Institute of Family Planning, Beijing, China, Graduate School of Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China, NHC Key Laboratory of Reproductive Health Engineering Technology Research (NRIFP), National Research Institute for Family Planning, Beijing, China
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Yun Zhu ,
Roles Funding acquisition, Supervision, Writing – review & editing
* E-mail: wbbahu@163.com (BW); zhuyun@ibp.ac.cn (YZ); chensr@bnu.edu.cn (SC)
Affiliation Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
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Su-Ren Chen
Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft
* E-mail: wbbahu@163.com (BW); zhuyun@ibp.ac.cn (YZ); chensr@bnu.edu.cn (SC)
Affiliation Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, China
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The core outer junction protein CFAP77 connects A- and B-tubules within doublet microtubules of cilia and flagella
- Lan Xia,
- Guo-Liang Yin,
- Yu Long,
- Fei Sun,
- Bin-Bin Wang,
- Yun Zhu,
- Su-Ren Chen
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- Published: October 21, 2025
- https://doi.org/10.1371/journal.pbio.3003442