Dopaminergic short axon cells integrate sensory and top–down inputs to enhance discriminative learning in the mouse olfactory bulb

Rahul Garg; Vikas Kumar; Jae Hyoun Seiler; Yunming Wu; Melainia McClain; Kexi Yi; C. Ron Yu

doi:10.1371/journal.pbio.3003375

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Peer-reviewed

Research Article

Dopaminergic short axon cells integrate sensory and top–down inputs to enhance discriminative learning in the mouse olfactory bulb

Rahul Garg,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

Affiliations Graduate School of Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
⨯
Vikas Kumar,

Roles Data curation, Formal analysis

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
⨯
Jae Hyoun Seiler,

Roles Methodology

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
⨯
Yunming Wu,

Roles Methodology

Affiliations Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America
⨯
Melainia McClain,

Roles Data curation

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
⨯
Kexi Yi,

Roles Data curation

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
⨯
C. Ron Yu

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: ron.yu@case.edu

Affiliations Graduate School of Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America, Department of Physiology and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, United States of America

https://orcid.org/0009-0009-8367-8848

⨯

Dopaminergic short axon cells integrate sensory and top–down inputs to enhance discriminative learning in the mouse olfactory bulb

Rahul Garg,
Vikas Kumar,
Jae Hyoun Seiler,
Yunming Wu,
Melainia McClain,
Kexi Yi,
C. Ron Yu

Published: September 16, 2025
https://doi.org/10.1371/journal.pbio.3003375

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Cholinergics
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Sensory perception
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Learning
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Olfactory bulb
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Axons
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