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Open Access
Peer-reviewed
Research Article
Lineage trajectories and fate determinants of postnatal neural stem cells and ependymal cells in the developing ventricular zone
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Jianqun Zheng ,
Contributed equally to this work with: Jianqun Zheng, Yawen Chen
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: zhengjianqun@ojlab.ac.cn (JZ); weihong@wmu.edu.cn (WS); chenx9@sustech.edu.cn (XC)
Affiliation Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yawen Chen ,
Contributed equally to this work with: Jianqun Zheng, Yawen Chen
Roles Data curation, Investigation, Methodology, Validation, Visualization, Writing – review & editing
Affiliation Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yukun Hu,
Roles Formal analysis, Investigation, Validation
Affiliation Shenzhen Key Laboratory of Gene Regulation and Systems Biology, Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China
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Yujian Zhu,
Roles Data curation, Investigation, Validation
Affiliation Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Jie Lin,
Roles Formal analysis, Investigation
Affiliation Shenzhen Key Laboratory of Gene Regulation and Systems Biology, Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China
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Manlin Xu,
Roles Investigation, Validation
Affiliation Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yunlong Zhang,
Roles Formal analysis
Affiliation Shenzhen Key Laboratory of Gene Regulation and Systems Biology, Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China
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Weihong Song ,
Roles Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: zhengjianqun@ojlab.ac.cn (JZ); weihong@wmu.edu.cn (WS); chenx9@sustech.edu.cn (XC)
Affiliation Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Xi Chen
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: zhengjianqun@ojlab.ac.cn (JZ); weihong@wmu.edu.cn (WS); chenx9@sustech.edu.cn (XC)
Affiliation Shenzhen Key Laboratory of Gene Regulation and Systems Biology, Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China
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Lineage trajectories and fate determinants of postnatal neural stem cells and ependymal cells in the developing ventricular zone
- Jianqun Zheng,
- Yawen Chen,
- Yukun Hu,
- Yujian Zhu,
- Jie Lin,
- Manlin Xu,
- Yunlong Zhang,
- Weihong Song,
- Xi Chen
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- Published: July 30, 2025
- https://doi.org/10.1371/journal.pbio.3003318