Quantitative modeling of multi-signal quorum-sensing maps environment to bacterial regulatory responses

Stephen Thomas; Ayatollah S. El-Zayat; James Gurney; Jennifer Rattray; Sam P. Brown

doi:10.1371/journal.pbio.3003316

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Open Access

Peer-reviewed

Research Article

Quantitative modeling of multi-signal quorum-sensing maps environment to bacterial regulatory responses

Stephen Thomas ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: stephen.thomas@gatech.edu (ST); sam.brown@biology.gatech.edu (SPB)

Affiliation School of Biological Sciences, Georgia Institute of Technology, Atlanta, GeorgiaUnited States of America

https://orcid.org/0000-0003-0773-0236

⨯
Ayatollah S. El-Zayat,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Microbiology, Faculty of Agriculture, Cairo University, Giza, Egypt
⨯
James Gurney,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GeorgiaUnited States of America
⨯
Jennifer Rattray,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – review & editing

Current address: Sandia National Laboratories, Albuquerque, New Mexico, USA.

Affiliation School of Biological Sciences, Georgia Institute of Technology, Atlanta, GeorgiaUnited States of America
⨯
Sam P. Brown

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: stephen.thomas@gatech.edu (ST); sam.brown@biology.gatech.edu (SPB)

Affiliation School of Biological Sciences, Georgia Institute of Technology, Atlanta, GeorgiaUnited States of America

https://orcid.org/0000-0003-1892-9275

⨯

Quantitative modeling of multi-signal quorum-sensing maps environment to bacterial regulatory responses

Stephen Thomas,
Ayatollah S. El-Zayat,
James Gurney,
Jennifer Rattray,
Sam P. Brown

Published: September 4, 2025
https://doi.org/10.1371/journal.pbio.3003316

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