Genome-wide identification of modulators of Chlamydia trachomatis parasitophorous vacuole stability highlights an important role for sphingolipid supply

• Mohammed Rizwan Babu Sait ,

  Contributed equally to this work with: Mohammed Rizwan Babu Sait, Lana H. Jachmann

  Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Lana H. Jachmann ,

  Contributed equally to this work with: Mohammed Rizwan Babu Sait, Lana H. Jachmann

  Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Gözde Türköz,

  Roles Formal analysis, Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Milica Milivojevic,

  Roles Formal analysis, Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Celia Llorente-Sáez,

  Roles Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Soniya Dhanjal,

  Roles Investigation

  Affiliation CRISPR Functional Genomics, SciLifeLab and Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden

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• Fabian Schumacher,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Institute of Pharmacy, Pharmacology and Toxicology, Freie Universität Berlin, Berlin, Germany

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• Sara Henriksson,

  Roles Investigation

  Affiliation Umeå Centre for Electron Microscopy (UCEM), Umeå University, Umeå, Sweden

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• Naga Venkata Gayathri Vegesna,

  Roles Investigation

  Affiliation Biochemical Imaging Centre Umeå (BICU), Umeå University, Umeå, Sweden

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• Noha Seddik,

  Roles Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Anastasiia Chaban,

  Roles Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Partha Mohanty,

  Roles Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Magnus Ölander,

  Roles Formal analysis, Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

  ⨯
• Samada Muraleedharan,

  Roles Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Sepideh Farmand Azadeh,

  Roles Investigation

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

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• Burkhard Kleuser,

  Roles Funding acquisition, Supervision

  Affiliation Institute of Pharmacy, Pharmacology and Toxicology, Freie Universität Berlin, Berlin, Germany

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• Bernhard Schmierer,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation CRISPR Functional Genomics, SciLifeLab and Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden

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•  [ ... ],
• Barbara S. Sixt

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: barbara.sixt@umu.se

  Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden

  https://orcid.org/0000-0002-5607-8902

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