Behavioral inflexibility through overtraining is mediated by reduced mGluR1/5 signaling capacity in the dorsolateral striatum

• Vincent Paget-Blanc ,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ These authors are co-first authors on this work.

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

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• Anna Cavaccini ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: cavaccini@hifo.uzh.ch (AC); raffaella.tonini@iit.it (RT)

  ¶‡ These authors are co-first authors on this work.

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

  ⨯
• Alessandra Longaretti,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

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• Luca Nava,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

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• Massimo Trusel,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

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• Anna Rocchi,

  Roles Investigation, Methodology

  Affiliation Neuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia, Genova, Italy

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• Maria Pennuto,

  Roles Funding acquisition, Methodology, Supervision

  Affiliations Department of Biomedical Sciences, University of Padova, Padova, Italy, Veneto Institute of Molecular Medicine (VIMM), Padova, Italy

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• Elena Marcello,

  Roles Funding acquisition, Investigation, Methodology

  Affiliation Department of Pharmacological and Biomolecular Sciences, University of Milano, Milano, Italy

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• Fabrizio Gardoni,

  Roles Funding acquisition, Investigation, Methodology, Supervision

  Affiliation Department of Pharmacological and Biomolecular Sciences, University of Milano, Milano, Italy

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• Barbara Greco,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

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• Raffaella Tonini

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: cavaccini@hifo.uzh.ch (AC); raffaella.tonini@iit.it (RT)

  Affiliation Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy

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