Phase separation of a PKA type I regulatory subunit regulates β-cell function through cAMP compartmentalization

• Ha Neul Lee ,

  Contributed equally to this work with: Ha Neul Lee, Julia C. Hardy

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America

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• Julia C. Hardy ,

  Contributed equally to this work with: Ha Neul Lee, Julia C. Hardy

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America, Shu-Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America

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• Emily H. Pool,

  Roles Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, United States of America

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• Jin-Fan Zhang,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America, Shu-Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America

  https://orcid.org/0000-0001-7145-7823

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• Su Hyun Kim,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America

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• William F. Buhl,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America

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• Jessica G.H. Bruystens,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America

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• Sohum Mehta,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America

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• Susan S. Taylor,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliations Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, United States of America

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• Jin Zhang

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jzhang32@ucsd.edu

  Affiliations Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America, Shu-Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, United States of America, Moores Cancer Center, University of California, San Diego, La Jolla, California, United States of America

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