STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins

Lin Xie; Lijuan Gao; Weihong Fu; Gangyun Wu; Hua Li; Wenxiu Ning

doi:10.1371/journal.pbio.3003227

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STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins

Lin Xie ,

Contributed equally to this work with: Lin Xie, Lijuan Gao, Weihong Fu

Roles Formal analysis, Investigation, Methodology, Validation, Visualization

Affiliation Yunnan Key Laboratory of Cell Metabolism and Diseases in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Lijuan Gao ,

Contributed equally to this work with: Lin Xie, Lijuan Gao, Weihong Fu

Roles Investigation, Methodology, Validation, Visualization

Affiliation Yunnan Key Laboratory of Cell Metabolism and Diseases in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Weihong Fu ,

Contributed equally to this work with: Lin Xie, Lijuan Gao, Weihong Fu

Roles Investigation, Methodology, Validation, Visualization

Affiliation Yunnan Key Laboratory of Cell Metabolism and Diseases in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Gangyun Wu,

Roles Validation

Affiliation Yunnan Key Laboratory of Cell Metabolism and Diseases in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Hua Li ,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: hualee@ynu.edu.cn (HL); wenxiu_ning@ynu.edu.cn (WN)

Affiliation Yunnan Key Laboratory of Cell Metabolism and Diseases in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China
⨯
Wenxiu Ning

Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: hualee@ynu.edu.cn (HL); wenxiu_ning@ynu.edu.cn (WN)

Affiliation Yunnan Key Laboratory of Cell Metabolism and Diseases in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China

https://orcid.org/0000-0003-1028-8151

⨯

STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins

Lin Xie,
Lijuan Gao,
Weihong Fu,
Gangyun Wu,
Hua Li,
Wenxiu Ning

Published: November 24, 2025
https://doi.org/10.1371/journal.pbio.3003227

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