Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythms and sleep

• Yuanqiang Sun ,

  Contributed equally to this work with: Yuanqiang Sun, Ke Shui

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation State Key Laboratory of Gene Function and Modulation Research, Center for Bioinformatics, School of Life Sciences, Peking University, Beijing, China

  ⨯
• Ke Shui ,

  Contributed equally to this work with: Yuanqiang Sun, Ke Shui

  Roles Data curation, Formal analysis, Investigation, Resources, Visualization, Writing – original draft, Writing – review & editing

  Affiliations College of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China, Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

  ⨯
• Qinyu Li,

  Roles Validation

  Affiliation Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

  ⨯
• Chenlu Liu,

  Roles Validation, Visualization

  Affiliation State Key Laboratory of Gene Function and Modulation Research, Center for Bioinformatics, School of Life Sciences, Peking University, Beijing, China

  ⨯
• Wanting Jin,

  Roles Investigation

  Affiliation State Key Laboratory of Gene Function and Modulation Research, Center for Bioinformatics, School of Life Sciences, Peking University, Beijing, China

  ⨯
• Jian-Quan Ni,

  Roles Resources

  Affiliation Gene Regulatory Lab, School of Medicine, Tsinghua University, Beijing, China

  ⨯
• Jian Lu ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: luj@pku.edu.cn (JL); zhangluoying@hust.edu.cn (LZ)

  Affiliations State Key Laboratory of Gene Function and Modulation Research, Center for Bioinformatics, School of Life Sciences, Peking University, Beijing, China, Beijing Advanced Center of RNA Biology (BEACON), Peking University, Beijing, China

  https://orcid.org/0000-0002-4409-1667

  ⨯
• Luoying Zhang

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

  * E-mail: luj@pku.edu.cn (JL); zhangluoying@hust.edu.cn (LZ)

  Affiliations Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China, Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, China

  https://orcid.org/0000-0001-5996-6975

  ⨯