The bacterial type three secretion system induces mechanoporation of vacuolar membranes

• Léa Swistak ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lea.swistak@embl.de (LS); matthijn.vos@pasteur.fr (MV); jost.enninga@pasteur.fr (JE)

  Current address: Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

  Affiliation Institut Pasteur, Université Paris Cité, CNRS UMR3691, Dynamics of Host-Pathogen Interactions Unit, Paris, France

  ⨯
• Marvin Albert,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Software, Validation, Visualization, Writing – review & editing

  Affiliation Institut Pasteur, Université Paris Cité, Image Analysis Hub, Paris, France

  ⨯
• Camila Valenzuela,

  Roles Investigation, Supervision, Visualization, Writing – review & editing

  Affiliation Institut Pasteur, Université Paris Cité, CNRS UMR3691, Dynamics of Host-Pathogen Interactions Unit, Paris, France

  ⨯
• Elif Begum Gokerkucuk,

  Roles Investigation, Methodology

  Affiliation Institut Pasteur, Université Paris Cité, CNRS UMR3691, Dynamics of Host-Pathogen Interactions Unit, Paris, France

  ⨯
• François Bontems,

  Roles Investigation, Methodology, Software, Supervision

  Affiliations Institut Pasteur, Université Paris Cité, CNRS UMR3569, Structural Virology, Paris, France, Département de Biologie et Chimie Structurales, Institut de Chimie des Substances Naturelles, CNRS UPR2301, Gif-sur-Yvette, France

  ⨯
• Stéphane Tachon,

  Roles Investigation, Methodology

  Affiliation Institut Pasteur, Université Paris Cité, NanoImaging Core Facility, Paris, France

  ⨯
• Keith T. Egger,

  Roles Investigation

  Affiliation Institut Pasteur, Université Paris Cité, CNRS UMR3691, Dynamics of Host-Pathogen Interactions Unit, Paris, France

  ⨯
• Anastasia D. Gazi,

  Roles Visualization

  Affiliation Institut Pasteur, Université Paris Cité, Ultrastructural BioImaging Core Facility, Paris, France

  ⨯
• Anna Sartori-Rupp,

  Roles Methodology

  Affiliation Institut Pasteur, Université Paris Cité, NanoImaging Core Facility, Paris, France

  ⨯
• Cammie F. Lesser,

  Roles Resources

  Affiliations Center for Bacterial Pathogenesis, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Perrine Paul-Gilloteaux,

  Roles Methodology

  Affiliation Nantes Université, CHU Nantes, CNRS, Inserm, BioCore, US16, SFR Bonamy, Nantes, France

  ⨯
• Jean-Yves Tinevez,

  Roles Conceptualization, Supervision

  Affiliation Institut Pasteur, Université Paris Cité, Image Analysis Hub, Paris, France

  ⨯
• Matthijn Vos ,

  Roles Supervision

  * E-mail: lea.swistak@embl.de (LS); matthijn.vos@pasteur.fr (MV); jost.enninga@pasteur.fr (JE)

  Affiliation Institut Pasteur, Université Paris Cité, NanoImaging Core Facility, Paris, France

  ⨯
• Jost Enninga

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Visualization, Writing – review & editing

  * E-mail: lea.swistak@embl.de (LS); matthijn.vos@pasteur.fr (MV); jost.enninga@pasteur.fr (JE)

  Affiliation Institut Pasteur, Université Paris Cité, CNRS UMR3691, Dynamics of Host-Pathogen Interactions Unit, Paris, France

  https://orcid.org/0000-0002-5218-349X

  ⨯