A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

• Iratxe Zuazo-Gaztelu,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• David Lawrence,

  Roles Data curation, Formal analysis

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Ioanna Oikonomidi,

  Roles Data curation, Formal analysis

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Scot Marsters,

  Roles Data curation, Formal analysis, Resources

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Ximo Pechuan-Jorge,

  Roles Data curation, Formal analysis, Software

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Catarina J. Gaspar,

  Roles Data curation, Formal analysis

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• David Kan,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of In Vivo Pharmacology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Ehud Segal,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of In Vivo Pharmacology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Kevin Clark,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Maureen Beresini,

  Roles Data curation, Formal analysis

  Affiliation Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Marie-Gabrielle Braun,

  Roles Resources

  Affiliation Department of Discovery Chemistry, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Joachim Rudolph,

  Roles Supervision

  Affiliation Department of Discovery Chemistry, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Zora Modrusan,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Proteomic and Genomic Technologies, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Meena Choi,

  Roles Data curation, Formal analysis, Software, Writing – review & editing

  Affiliation Department of Proteomic and Genomic Technologies, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Wendy Sandoval,

  Roles Data curation, Formal analysis

  Affiliation Department of Proteomic and Genomic Technologies, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Mike Reichelt,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Pathology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• David C. DeWitt,

  Roles Methodology, Software, Visualization

  Affiliation Department of Pathology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• Pekka Kujala,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Center for Molecular Medicine—Cell Biology, University Medical Center, Utrecht, The Netherlands

  ⨯
• Suzanne van Dijk,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Center for Molecular Medicine—Cell Biology, University Medical Center, Utrecht, The Netherlands

  ⨯
• Judith Klumperman,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation Center for Molecular Medicine—Cell Biology, University Medical Center, Utrecht, The Netherlands

  ⨯
•  [ ... ],
• Avi Ashkenazi

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: aa@gene.com

  Affiliation Department of Research Oncology, Genentech, Inc., South San Francisco, California, United States of America

  ⨯
• [ view all ]
• [ view less ]