Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid

• Seong H. Chow,

  Roles Conceptualization, Data curation, Investigation, Supervision, Writing – original draft

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Yusun Jeon,

  Roles Data curation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Pankaj Deo,

  Roles Data curation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Amy T. Y. Yeung,

  Roles Data curation

  Affiliation The Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom

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• Christine Hale,

  Roles Data curation

  Affiliations The Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom, Department of Medicine, Addenbrookes Hospital, Cambridge, United Kingdom

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• Sushmita Sridhar,

  Roles Data curation

  Affiliations The Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom, Department of Medicine, Addenbrookes Hospital, Cambridge, United Kingdom

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• Gilu Abraham,

  Roles Data curation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Joshua Nickson,

  Roles Data curation, Investigation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Françios A. B. Olivier,

  Roles Data curation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Jhih-Hang Jiang,

  Roles Data curation

  Affiliations Department of Microbiology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia

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• Yue Ding,

  Roles Data curation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Department of Materials Science and Engineering, Faculty of Engineering, Monash University, Clayton, Australia

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• Mei-Ling Han,

  Roles Data curation

  Affiliation Department of Microbiology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia

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• Anton P. Le Brun,

  Roles Data curation

  Affiliation Australian Centre for Neutron Scattering, Australian Nuclear Science and Technology Organisation, Kirrawee DC, Australia

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• Dovile Anderson,

  Roles Data curation

  Affiliation Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia

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• Darren Creek,

  Roles Data curation

  Affiliation Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia

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• Janette Tong,

  Roles Data curation

  Affiliation Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia

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• Kip Gabriel,

  Roles Data curation

  Affiliation Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia

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• Jian Li,

  Roles Supervision

  Affiliations Centre to Impact AMR, Monash University, Clayton, Australia, Department of Microbiology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia

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• Ana Traven,

  Roles Data curation

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

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• Gordon Dougan,

  Roles Data curation

  Affiliations The Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom, Department of Medicine, Addenbrookes Hospital, Cambridge, United Kingdom

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• Hsin-Hui Shen ,

  Roles Data curation, Funding acquisition, Methodology, Supervision

  * E-mail: hsin-hui.shen@monash.edu (H-HS); thomas.naderer@monash.edu (TN)

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Department of Materials Science and Engineering, Faculty of Engineering, Monash University, Clayton, Australia

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•  [ ... ],
• Thomas Naderer

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft

  * E-mail: hsin-hui.shen@monash.edu (H-HS); thomas.naderer@monash.edu (TN)

  Affiliations Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia, Centre to Impact AMR, Monash University, Clayton, Australia

  https://orcid.org/0000-0003-2691-0283

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