CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells

• Bianca Pellegrino,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

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• Keren David,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

  ⨯
• Stav Rabani,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

  ⨯
• Bar Lampert,

  Roles Data curation

  Affiliation Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

  ⨯
• Thuy Tran,

  Roles Data curation, Investigation

  Affiliation Yale Cancer Center and School of Medicine, New Haven, Connecticut, United States of America

  ⨯
• Edward Doherty,

  Roles Data curation, Formal analysis

  Affiliation Yale Cancer Center and School of Medicine, New Haven, Connecticut, United States of America

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• Marta Piecychna,

  Roles Data curation, Formal analysis

  Affiliation Yale Cancer Center and School of Medicine, New Haven, Connecticut, United States of America

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• Roberto Meza-Romero,

  Roles Methodology, Resources

  Affiliations Neuroimmunology Research, VA Portland Health Care System, Portland, Oregon, United States of America, Department of Neurology, Oregon Health & Science University, Portland, Oregon, United States of America, Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, United States of America

  ⨯
• Lin Leng,

  Roles Methodology, Resources

  Affiliation Yale Cancer Center and School of Medicine, New Haven, Connecticut, United States of America

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• Dov Hershkovitz,

  Affiliation Insitute of Pathology, Sourasky Medical Center, Tel Aviv, Israel

  ⨯
• Arthur A. Vandenbark,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations Neuroimmunology Research, VA Portland Health Care System, Portland, Oregon, United States of America, Department of Neurology, Oregon Health & Science University, Portland, Oregon, United States of America, Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, United States of America

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• Richard Bucala,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliation Yale Cancer Center and School of Medicine, New Haven, Connecticut, United States of America

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• Shirly Becker-Herman,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

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• Idit Shachar

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – original draft

  * E-mail: idit.shachar@weizmann.ac.il

  Affiliation Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

  https://orcid.org/0000-0003-0004-6159

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