Elevated vesicular Zn²⁺ in dorsal root ganglion neurons expressing the transporter TMEM163 causes age-associated itchy skin in mice

• Fang Tong ,

  Contributed equally to this work with: Fang Tong, Shuai Liu, Chen Zhang

  Roles Data curation, Formal analysis, Visualization

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Shuai Liu ,

  Contributed equally to this work with: Fang Tong, Shuai Liu, Chen Zhang

  Roles Investigation, Methodology

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Chen Zhang ,

  Contributed equally to this work with: Fang Tong, Shuai Liu, Chen Zhang

  Roles Methodology, Resources

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Xicheng Gu,

  Roles Formal analysis, Methodology

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Huan Yang,

  Roles Data curation

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Bin Zhou,

  Roles Investigation

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Yun-Yun Wang,

  Roles Resources

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Jianwei Chen,

  Roles Resources

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Qianhui Qu,

  Roles Conceptualization

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Ye Gong,

  Roles Conceptualization

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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• Haili Pan,

  Roles Resources

  Affiliation Neurological Institute of Jiangxi Province and Department of Neurology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China

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• Chen Liang,

  Roles Investigation, Methodology

  Affiliation Guangdong Institute of Intelligence Science and Technology, Hengqin, Zhuhai, China

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• Changlin Li,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation Guangdong Institute of Intelligence Science and Technology, Hengqin, Zhuhai, China

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• Xin Zhang ,

  Roles Conceptualization

  * E-mail: xinzhang3@njmu.edu.cn (XZ); qingjianhan@fudan.edu.cn (QH)

  Affiliation The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi People’s Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China

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• Qingjian Han

  Roles Writing – original draft, Writing – review & editing

  * E-mail: xinzhang3@njmu.edu.cn (XZ); qingjianhan@fudan.edu.cn (QH)

  Affiliation Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

  https://orcid.org/0000-0001-6641-7499

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