Polygenic scores for complex traits are associated with changes in concentration of circulating lipid species

• Rubina Tabassum ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  * E-mail: rubina.tabassum@helsinki.fi (RT); samuli.ripatti@helsinki.fi (SR)

  Affiliation Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland

  https://orcid.org/0000-0002-3120-3041

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• Nina Mars,

  Roles Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America

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• Pietro Della Briotta Parolo,

  Roles Formal analysis, Writing – review & editing

  Affiliation Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland

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• Mathias J. Gerl,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Lipotype GmbH, Dresden, Germany

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• Christian Klose,

  Roles Methodology, Writing – review & editing

  Affiliation Lipotype GmbH, Dresden, Germany

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• FinnGen ,

  ¶Membership of FinnGen is provided in S1 Text.

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• Matti Pirinen,

  Roles Methodology, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland, Department of Public Health, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland

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• Kai Simons,

  Roles Methodology, Writing – review & editing

  Affiliation Lipotype GmbH, Dresden, Germany

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• Elisabeth Widén,

  Roles Resources, Writing – review & editing

  Affiliation Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland

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• Samuli Ripatti

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: rubina.tabassum@helsinki.fi (RT); samuli.ripatti@helsinki.fi (SR)

  Affiliations Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America, Department of Public Health, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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