Mycobacteria that cause tuberculosis have retained ancestrally acquired genes for the biosynthesis of chemically diverse terpene nucleosides

• Jacob A. Mayfield,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-5762-6755

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• Sahadevan Raman,

  Roles Investigation, Methodology, Validation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Alexandrea K. Ramnarine,

  Roles Investigation, Validation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Vivek K. Mishra,

  Roles Investigation, Validation

  Current address: Pranveer Singh Institute of Technology, Kanpur, India

  Affiliation Stratingh Institute for Chemistry, University of Groningen, Groningen, the Netherlands

  ⨯
• Annie D. Huang,

  Roles Investigation, Validation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Sandrine Dudoit,

  Roles Methodology, Resources, Software, Visualization, Writing – review & editing

  Affiliations Division of Biostatistics, School of Public Health, University of California, Berkeley, California, United States of America, Department of Statistics, University of California, Berkeley, California, United States of America

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• Jeffrey Buter,

  Roles Conceptualization, Investigation

  Current address: Hanze University of Applied Sciences, Institute for Life Science & Technology, Groningen, the Netherlands

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Tan-Yun Cheng,

  Roles Investigation, Methodology, Validation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• David C. Young,

  Roles Conceptualization, Investigation, Methodology, Validation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Yashodhan M. Nair,

  Roles Investigation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Isobel G. Ouellet,

  Roles Investigation

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Braden T. Griebel,

  Roles Formal analysis, Investigation, Methodology

  Affiliations University of Washington Department of Chemical Engineering, Seattle, Washington State, United States of America, Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington State, United States of America

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• Shuyi Ma,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations University of Washington Department of Chemical Engineering, Seattle, Washington State, United States of America, Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington State, United States of America, University of Washington Department of Pediatrics, Seattle, Washington State, United States of America, University of Washington Pathobiology Program, Department of Global Health, Seattle, Washington State, United States of America

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• David R. Sherman,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Microbiology, University of Washington, Seattle, Washington State, United States of America

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• Ludovic Mallet,

  Roles Formal analysis, Investigation, Methodology, Visualization

  Affiliation Unité de Mathématique et Informatique Appliquées de Toulouse, INRA, Castanet-Tolosan, France

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• Kyu Y. Rhee,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Infectious Diseases, Weill Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America

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• Adriaan J. Minnaard,

  Roles Investigation, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Stratingh Institute for Chemistry, University of Groningen, Groningen, the Netherlands

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•  [ ... ],
• D. Branch Moody

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: bmoody@bwh.harvard.edu

  Affiliation Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0003-2306-3058

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