Bats generate lower affinity but higher diversity antibody responses than those of mice, but pathogen-binding capacity increases if protein is restricted in their diet

• Daniel E. Crowley ,

  Contributed equally to this work with: Daniel E. Crowley, Caylee A. Falvo

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: dc778@cornell.edu

  Affiliations Department of Public and Ecosystem Health, Cornell University, Ithaca, New York, United States of America, Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  https://orcid.org/0000-0003-4262-253X

  ⨯
• Caylee A. Falvo ,

  Contributed equally to this work with: Daniel E. Crowley, Caylee A. Falvo

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliations Department of Public and Ecosystem Health, Cornell University, Ithaca, New York, United States of America, Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  ⨯
• Evelyn Benson,

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  ⨯
• Jodi Hedges,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  ⨯
• Mark Jutila,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  ⨯
• Shahrzad Ezzatpour,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

  ⨯
• Hector C. Aguilar,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

  ⨯
• Manuel Ruiz-Aravena,

  Roles Conceptualization, Visualization, Writing – review & editing

  Affiliation Department of Public and Ecosystem Health, Cornell University, Ithaca, New York, United States of America

  ⨯
• Wenjun Ma,

  Roles Resources, Writing – review & editing

  Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine, and Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America

  ⨯
• Tony Schountz,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Writing – review & editing

  Affiliation Center for Vector-borne Infectious Diseases, Department of Microbiology, Immunology, and Pathology Colorado State University, Fort Collins, Colorado, United States of America

  ⨯
• Agnieszka Rynda-Apple ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  ⨯
• Raina K. Plowright

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Department of Public and Ecosystem Health, Cornell University, Ithaca, New York, United States of America, Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States of America

  ⨯