An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection

• Jobran Chebib,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Anika Jonas,

  Roles Investigation

  Affiliation Department for Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany

  ⨯
• Eugenio López-Cortegano,

  Roles Formal analysis, Writing – review & editing

  Affiliation Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Sven Künzel,

  Roles Investigation

  Affiliation Department for Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany

  ⨯
• Diethard Tautz,

  Roles Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department for Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany

  ⨯
• Peter D. Keightley

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: peter.keightley@ed.ac.uk

  Affiliation Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0001-8129-2794

  ⨯