Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation response

Ayush Aggarwal; Ayesha Nasreen; Babita Sharma; Sarthak Sahoo; Keerthic Aswin; Mohammed Faruq; Rajesh Pandey; Mohit K. Jolly; Abhyudai Singh; Rajesh S. Gokhale; Vivek T. Natarajan

doi:10.1371/journal.pbio.3002776

Loading metrics

Open Access

Peer-reviewed

Research Article

Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation response

Ayush Aggarwal,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
⨯
Ayesha Nasreen,

Roles Investigation, Visualization, Writing – review & editing

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
⨯
Babita Sharma,

Roles Investigation

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
⨯
Sarthak Sahoo,

Roles Formal analysis, Methodology, Visualization

Affiliation Department of Bioengineering, Indian Institute of Science, Bangalore, India
⨯
Keerthic Aswin,

Roles Investigation, Visualization, Writing – review & editing

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
⨯
Mohammed Faruq,

Roles Methodology, Resources

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
⨯
Rajesh Pandey,

Roles Methodology, Resources

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
⨯
Mohit K. Jolly,

Roles Methodology, Supervision

Affiliation Department of Bioengineering, Indian Institute of Science, Bangalore, India
⨯
Abhyudai Singh,

Roles Methodology, Supervision

Affiliations Electrical and Computer Engineering, University of Delaware, Newark, Delaware, United States of America, Biomedical Engineering, University of Delaware, Newark, Delaware, United States of America
⨯
Rajesh S. Gokhale,

Roles Conceptualization

Affiliations National Institute of Immunology, New Delhi, India, Indian Institute of Science Education and Research Pune, Pune, India
⨯
Vivek T. Natarajan

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: tnvivek@igib.in

Affiliations CSIR-Institute of Genomics and Integrative Biology, New Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India

https://orcid.org/0000-0002-8537-5471

⨯

Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation response

Ayush Aggarwal,
Ayesha Nasreen,
Babita Sharma,
Sarthak Sahoo,
Keerthic Aswin,
Mohammed Faruq,
Rajesh Pandey,
Mohit K. Jolly,
Abhyudai Singh,
Rajesh S. Gokhale

Published: August 20, 2024
https://doi.org/10.1371/journal.pbio.3002776

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Melanocytes
Is the Subject Area "Melanocytes" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
B16 cells
Is the Subject Area "B16 cells" applicable to this article?

Thanks for your feedback.
Pigments
Is the Subject Area "Pigments" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
RNA sequencing
Is the Subject Area "RNA sequencing" applicable to this article?

Thanks for your feedback.
Cell cycle and cell division
Is the Subject Area "Cell cycle and cell division" applicable to this article?

Thanks for your feedback.
Skin
Is the Subject Area "Skin" applicable to this article?

Thanks for your feedback.