Chemical modulation of gut bacterial metabolism induces colanic acid and extends the lifespan of nematode and mammalian hosts

• Guo Hu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

  https://orcid.org/0000-0003-0597-208X

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• Marzia Savini,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

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• Matthew Brandon Cooke,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Xin Wei,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China

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• Dinghuan Deng,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization

  Affiliation Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

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• Shihong M. Gao,

  Roles Formal analysis, Methodology, Visualization

  Affiliation Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

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• Ruyue Alps Xia,

  Roles Formal analysis, Software, Visualization, Writing – review & editing

  Affiliation Riverside High School, Ashburn, Virginia, United States of America

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• Youchen Guan,

  Roles Data curation, Investigation

  Affiliation Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

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• Alice X. Wen,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Xin Yu,

  Roles Data curation

  Affiliation Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, United States of America

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• Jin Wang,

  Roles Conceptualization, Data curation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, United States of America

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• Chao Jiang,

  Roles Conceptualization, Methodology, Supervision

  Affiliation Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China

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• Christophe Herman,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Jiefu Li,

  Roles Conceptualization, Supervision

  Affiliation Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

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• Meng C. Wang

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: mengwang@janelia.hhmi.org

  Affiliation Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

  https://orcid.org/0000-0002-5898-6007

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