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GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade
- Madison F. Walker ,
- Jingyi Zhang ,
- William Steiner ,
- Pei-I Ku ,
- Ju-Fen Zhu,
- Zachary Michaelson,
- Yu-Chen Yen,
- Annabel Lee,
- Alyssa B. Long,
- Mattie J. Casey,
- Abhishek Poddar,
- Isaac B. Nelson,
- Corvin D. Arveseth,
- Falko Nagel,
- Ryan Clough,
- Sarah LaPotin,
- Kristen M. Kwan,
- Stefan Schulz,
- Rodney A. Stewart,
- John J. G. Tesmer,
- Tamara Caspary,
- Radhika Subramanian ,
-
Xuecai Ge ,
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft
* E-mail: radhika@molbio.mgh.harvard.edu (RS); xge2@ucmerced.edu (XG); benjamin.myers@hci.utah.edu (BRM)
Affiliation Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, United States of America
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Benjamin R. Myers
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft
* E-mail: radhika@molbio.mgh.harvard.edu (RS); xge2@ucmerced.edu (XG); benjamin.myers@hci.utah.edu (BRM)
Affiliations Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
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https://orcid.org/0000-0002-5896-0800
GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade
- Madison F. Walker,
- Jingyi Zhang,
- William Steiner,
- Pei-I Ku,
- Ju-Fen Zhu,
- Zachary Michaelson,
- Yu-Chen Yen,
- Annabel Lee,
- Alyssa B. Long,
- Mattie J. Casey
- Published: August 13, 2024
- https://doi.org/10.1371/journal.pbio.3002685