The clock-like accumulation of germline and somatic mutations can arise from the interplay of DNA damage and repair

• Natanael Spisak ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: natanael.spisak@gmail.com

  Affiliation Department of Biological Sciences, Columbia University, New York, New York, United States of America

  https://orcid.org/0000-0002-6332-047X

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• Marc de Manuel,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biological Sciences, Columbia University, New York, New York, United States of America

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• William Milligan,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Biological Sciences, Columbia University, New York, New York, United States of America

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• Guy Sella,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Biological Sciences, Columbia University, New York, New York, United States of America, Program for Mathematical Genomics, Columbia University, New York, New York, United States of America

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• Molly Przeworski

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biological Sciences, Columbia University, New York, New York, United States of America, Department of Systems Biology, Columbia University, New York, New York, United States of America

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