Analysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applications

• Benjamin V. Ineichen ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft

  * E-mail: benjamin.ineichen@uzh.ch

  Affiliations Centre for Reproducible Science, University of Zurich, Zurich, Switzerland, Clinical Neuroscience Center, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0003-1362-4819

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• Eva Furrer,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Centre for Reproducible Science, University of Zurich, Zurich, Switzerland

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• Servan L. Grüninger,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliations Centre for Reproducible Science, University of Zurich, Zurich, Switzerland, Department of Mathematics, University of Zurich, Zurich, Switzerland

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• Wolfgang E. Zürrer,

  Roles Data curation, Writing – review & editing

  Affiliation Centre for Reproducible Science, University of Zurich, Zurich, Switzerland

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• Malcolm R. Macleod

  Roles Conceptualization, Methodology, Supervision, Writing – original draft

  Affiliation Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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