FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis

Jing Xu; Rongtian Guo; Nasi Wen; Luping Li; Yong Yi; Jingzhen Chen; Zongyu He; Jian Yang; Zhi-Xiong Jim Xiao; Mengmeng Niu

doi:10.1371/journal.pbio.3002446

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Open Access

Peer-reviewed

Research Article

FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis

Jing Xu,

Roles Data curation, Formal analysis, Project administration, Validation, Writing – original draft

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Rongtian Guo,

Roles Data curation, Investigation, Methodology

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Nasi Wen,

Roles Data curation, Investigation

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Luping Li,

Roles Data curation, Formal analysis, Investigation

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Yong Yi,

Roles Data curation, Investigation

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Jingzhen Chen,

Roles Data curation, Investigation, Methodology

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Zongyu He,

Roles Data curation, Investigation, Methodology

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Jian Yang,

Roles Data curation, Investigation, Methodology

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Zhi-Xiong Jim Xiao,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China
⨯
Mengmeng Niu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Validation, Writing – original draft, Writing – review & editing

* E-mail: niumm@scu.edu.cn

Affiliation Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China

https://orcid.org/0000-0002-0940-4672

⨯

FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis

Jing Xu,
Rongtian Guo,
Nasi Wen,
Luping Li,
Yong Yi,
Jingzhen Chen,
Zongyu He,
Jian Yang,
Zhi-Xiong Jim Xiao,
Mengmeng Niu

Published: December 22, 2023
https://doi.org/10.1371/journal.pbio.3002446

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