Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing

• Francisco Nualart ,

  Contributed equally to this work with: Francisco Nualart, Manuel Cifuentes

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: frnualart@udec.cl (FN); mcifuentes@uma.es (MC); katterinsalazar@udec.cl (KS)

  Affiliations Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepcion, Concepcion, Chile, Center for Advanced Microscopy CMA BIO BIO, University of Concepcion, Concepcion, Chile

  https://orcid.org/0000-0002-7762-1417

  ⨯
• Manuel Cifuentes ,

  Contributed equally to this work with: Francisco Nualart, Manuel Cifuentes

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: frnualart@udec.cl (FN); mcifuentes@uma.es (MC); katterinsalazar@udec.cl (KS)

  Affiliation Department of Cell Biology, Genetics and Physiology, University of Malaga, Málaga Biomedical Research Institute and Nanomedicine Platform (IBIMA-BIONAND Platform), Malaga, Spain

  https://orcid.org/0000-0003-1414-469X

  ⨯
• Eder Ramírez,

  Roles Formal analysis, Investigation, Methodology, Software, Validation

  Affiliation Center for Advanced Microscopy CMA BIO BIO, University of Concepcion, Concepcion, Chile

  ⨯
• Fernando Martínez,

  Roles Funding acquisition, Investigation, Methodology, Project administration, Supervision

  Affiliation Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepcion, Concepcion, Chile

  ⨯
• María José Barahona,

  Roles Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Center for Advanced Microscopy CMA BIO BIO, University of Concepcion, Concepcion, Chile

  ⨯
• Luciano Ferrada,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Center for Advanced Microscopy CMA BIO BIO, University of Concepcion, Concepcion, Chile

  ⨯
• Natalia Saldivia,

  Roles Investigation, Methodology

  Affiliation Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepcion, Concepcion, Chile

  ⨯
• Ernesto R. Bongarzone,

  Roles Funding acquisition, Investigation, Resources

  Affiliation Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Bernard Thorens,

  Roles Funding acquisition, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

  ⨯
• Katterine Salazar

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: frnualart@udec.cl (FN); mcifuentes@uma.es (MC); katterinsalazar@udec.cl (KS)

  Affiliation Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepcion, Concepcion, Chile

  ⨯