Functional unknomics: Systematic screening of conserved genes of unknown function

João J. Rocha; Satish Arcot Jayaram; Tim J. Stevens; Nadine Muschalik; Rajen D. Shah; Sahar Emran; Cristina Robles; Matthew Freeman; Sean Munro

doi:10.1371/journal.pbio.3002222

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Open Access

Peer-reviewed

Research Article

Functional unknomics: Systematic screening of conserved genes of unknown function

João J. Rocha ,

Contributed equally to this work with: João J. Rocha, Satish Arcot Jayaram, Tim J. Stevens, Nadine Muschalik

Roles Investigation, Methodology, Project administration, Software

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Satish Arcot Jayaram ,

Contributed equally to this work with: João J. Rocha, Satish Arcot Jayaram, Tim J. Stevens, Nadine Muschalik

Roles Investigation, Methodology

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Tim J. Stevens ,

Contributed equally to this work with: João J. Rocha, Satish Arcot Jayaram, Tim J. Stevens, Nadine Muschalik

Roles Formal analysis, Software, Visualization

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Nadine Muschalik ,

Contributed equally to this work with: João J. Rocha, Satish Arcot Jayaram, Tim J. Stevens, Nadine Muschalik

Roles Investigation, Validation

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Rajen D. Shah,

Roles Formal analysis, Methodology

Affiliation Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom
⨯
Sahar Emran,

Roles Investigation

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Cristina Robles,

Roles Investigation

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Matthew Freeman ,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: matthew.freeman@path.ox.ac.uk (MF); sean@mrc-lmb.cam.ac.uk (SM)

Affiliations MRC Laboratory of Molecular Biology, Cambridge, United Kingdom, Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

https://orcid.org/0000-0003-0410-5451

⨯
Sean Munro

Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: matthew.freeman@path.ox.ac.uk (MF); sean@mrc-lmb.cam.ac.uk (SM)

Affiliation MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

https://orcid.org/0000-0001-6160-5773

⨯

Functional unknomics: Systematic screening of conserved genes of unknown function

João J. Rocha,
Satish Arcot Jayaram,
Tim J. Stevens,
Nadine Muschalik,
Rajen D. Shah,
Sahar Emran,
Cristina Robles,
Matthew Freeman,
Sean Munro

Published: August 8, 2023
https://doi.org/10.1371/journal.pbio.3002222

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