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Open Access
Peer-reviewed
Research Article
Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization
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Pinyi Liu ,
Contributed equally to this work with: Pinyi Liu, Yan Chen, Zhi Zhang
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Yan Chen ,
Contributed equally to this work with: Pinyi Liu, Yan Chen, Zhi Zhang
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Zhi Zhang ,
Contributed equally to this work with: Pinyi Liu, Yan Chen, Zhi Zhang
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Zengqiang Yuan,
Roles Investigation, Methodology
Affiliations The Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing, China, Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China
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Jian-Guang Sun,
Roles Investigation, Methodology
Affiliations The Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing, China, Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China
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Shengnan Xia,
Roles Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Xiang Cao,
Roles Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Jian Chen,
Roles Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Cun-Jin Zhang,
Roles Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Yanting Chen,
Roles Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Hui Zhan,
Roles Investigation, Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Yuexinzi Jin,
Roles Investigation
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Xinyu Bao,
Roles Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Yue Gu,
Roles Methodology
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Meijuan Zhang,
Roles Investigation
Affiliation Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Yun Xu
Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing
* E-mail: xuyun20042001@aliyun.com
Affiliations Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China, Jiangsu Province Stroke Center for Diagnosis and Therapy, Nanjing, China, Nanjing Neurology Clinic Medical Center, Nanjing, China, Institute of Brain Sciences, Nanjing University, Nanjing, China, Jiangsu Key Laboratory for Molecular Medicine, Medical School of Nanjing University, Nanjing, China
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Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization
- Pinyi Liu,
- Yan Chen,
- Zhi Zhang,
- Zengqiang Yuan,
- Jian-Guang Sun,
- Shengnan Xia,
- Xiang Cao,
- Jian Chen,
- Cun-Jin Zhang,
- Yanting Chen
- Published: July 24, 2023
- https://doi.org/10.1371/journal.pbio.3002199