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Open Access
Peer-reviewed
Research Article
A systematic CRISPR screen reveals redundant and specific roles for Dscam1 isoform diversity in neuronal wiring
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Haiyang Dong ,
Contributed equally to this work with: Haiyang Dong, Xi Yang, Lili Wu
Roles Data curation, Formal analysis, Funding acquisition, Investigation, Validation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Xi Yang ,
Contributed equally to this work with: Haiyang Dong, Xi Yang, Lili Wu
Roles Data curation, Formal analysis, Validation
Affiliation Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
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Lili Wu ,
Contributed equally to this work with: Haiyang Dong, Xi Yang, Lili Wu
Roles Data curation, Formal analysis, Investigation, Validation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Shixin Zhang,
Roles Data curation, Formal analysis, Investigation, Validation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Jian Zhang,
Roles Data curation, Formal analysis, Investigation, Validation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Pengjuan Guo,
Roles Data curation, Formal analysis, Investigation, Validation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Yiwen Du,
Roles Data curation, Formal analysis, Validation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Changkun Pan,
Roles Data curation
Affiliation Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
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Ying Fu,
Roles Data curation, Formal analysis
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Lei Li,
Roles Data curation, Formal analysis
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Jilong Shi,
Roles Data curation, Formal analysis
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Yanda Zhu,
Roles Data curation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Hongru Ma,
Roles Data curation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Lina Bian,
Roles Data curation
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Bingbing Xu,
Roles Data curation, Formal analysis
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Guo Li,
Roles Data curation, Formal analysis
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Feng Shi,
Roles Data curation, Formal analysis
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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Jianhua Huang,
Roles Formal analysis, Resources, Validation
Affiliation Institute of Insect Sciences, Zhejiang University, Hangzhou, Zhejiang, China, PR China
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Haihuai He ,
Roles Data curation, Formal analysis, Funding acquisition, Resources, Validation
* E-mail: haihuai.he@scu.edu.cn (HH); jinyf@zju.edu.cn (YJ)
Affiliation Department of Neurosurgery, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
⨯ - [ ... ],
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Yongfeng Jin
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Validation, Writing – original draft
* E-mail: haihuai.he@scu.edu.cn (HH); jinyf@zju.edu.cn (YJ)
Affiliation MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
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A systematic CRISPR screen reveals redundant and specific roles for Dscam1 isoform diversity in neuronal wiring
- Haiyang Dong,
- Xi Yang,
- Lili Wu,
- Shixin Zhang,
- Jian Zhang,
- Pengjuan Guo,
- Yiwen Du,
- Changkun Pan,
- Ying Fu,
- Lei Li
- Published: July 6, 2023
- https://doi.org/10.1371/journal.pbio.3002197