Identification of a novel lipoic acid biosynthesis pathway reveals the complex evolution of lipoate assembly in prokaryotes

Tomohisa Sebastian Tanabe; Martina Grosser; Lea Hahn; Carolin Kümpel; Hanna Hartenfels; Evelyn Vtulkin; Wanda Flegler; Christiane Dahl

doi:10.1371/journal.pbio.3002177

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Peer-reviewed

Research Article

Identification of a novel lipoic acid biosynthesis pathway reveals the complex evolution of lipoate assembly in prokaryotes

Tomohisa Sebastian Tanabe,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Martina Grosser,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Lea Hahn,

Roles Data curation, Investigation

Current address: Institut für Integrierte Naturwissenschaften, Arbeitsgruppe Mikrobiologie, Universität Koblenz, Koblenz, Germany

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Carolin Kümpel,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Hanna Hartenfels,

Roles Investigation

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Evelyn Vtulkin,

Roles Investigation

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Wanda Flegler,

Roles Investigation

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Christiane Dahl

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft

* E-mail: chdahl@uni-bonn.de

Affiliation Institut für Mikrobiologie & Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

https://orcid.org/0000-0001-8288-7546

⨯

Identification of a novel lipoic acid biosynthesis pathway reveals the complex evolution of lipoate assembly in prokaryotes

Tomohisa Sebastian Tanabe,
Martina Grosser,
Lea Hahn,
Carolin Kümpel,
Hanna Hartenfels,
Evelyn Vtulkin,
Wanda Flegler,
Christiane Dahl

Published: June 27, 2023
https://doi.org/10.1371/journal.pbio.3002177

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