Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span

• Zhongliang Hu ,

  Contributed equally to this work with: Zhongliang Hu, Yamei Luo, Yuting Liu

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

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• Yamei Luo ,

  Contributed equally to this work with: Zhongliang Hu, Yamei Luo, Yuting Liu

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

  ⨯
• Yuting Liu ,

  Contributed equally to this work with: Zhongliang Hu, Yamei Luo, Yuting Liu

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

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• Yaru Luo,

  Roles Data curation, Formal analysis

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

  ⨯
• Liangce Wang,

  Roles Data curation, Formal analysis

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

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• Shengsong Gou,

  Roles Resources

  Affiliation Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China

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• Yuling Peng,

  Roles Data curation, Formal analysis

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

  ⨯
• Rui Wei,

  Roles Data curation, Formal analysis

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

  ⨯
• Da Jia,

  Roles Resources, Writing – review & editing

  Affiliation Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China

  ⨯
• Yuan Wang,

  Roles Resources, Writing – review & editing

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

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• Shangbang Gao ,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: sgao@hust.edu.cn (SG); yanzhang@scu.edu.cn (YZ)

  Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

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• Yan Zhang

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: sgao@hust.edu.cn (SG); yanzhang@scu.edu.cn (YZ)

  Affiliation National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

  https://orcid.org/0000-0002-6041-4454

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