Statistical simulations show that scientists need not increase overall sample size by default when including both sexes in in vivo studies

• Benjamin Phillips,

  Roles Conceptualization, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Data Sciences & Quantitative Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdom

  https://orcid.org/0000-0001-9161-8903

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• Timo N. Haschler,

  Roles Data curation, Writing – review & editing

  Affiliation Bioscience Renal, Research and Early Development Cardiovascular, Renal and Metabolism, Biopharmaceutical R&D, AstraZeneca, Cambridge, United Kingdom

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• Natasha A. Karp

  Roles Conceptualization, Formal analysis, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: natasha.karp@astrazeneca.com

  Affiliation Data Sciences & Quantitative Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdom

  https://orcid.org/0000-0002-8404-2907

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