Targeting AAV vectors to the central nervous system by engineering capsid–receptor interactions that enable crossing of the blood–brain barrier

• Qin Huang,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Albert T. Chen,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Biological and Biomedical Sciences, Harvard University, Cambridge, Massachusetts, United States of America

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• Ken Y. Chan,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Hikari Sorensen,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Andrew J. Barry,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Bahar Azari,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Electrical & Computer Engineering Department, Northeastern University, Boston, Massachusetts, United States of America

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• Qingxia Zheng,

  Roles Investigation

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Thomas Beddow,

  Roles Investigation

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Binhui Zhao,

  Roles Investigation

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Isabelle G. Tobey,

  Roles Investigation

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Cynthia Moncada-Reid,

  Roles Investigation

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Fatma-Elzahraa Eid,

  Roles Conceptualization, Formal analysis, Methodology

  Affiliations Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Systems and Computer Engineering, Al-Azhar University, Cairo, Egypt

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• Christopher J. Walkey,

  Roles Formal analysis, Investigation

  Affiliation Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States of America

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• M. Cecilia Ljungberg,

  Roles Investigation

  Affiliations Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, Texas, United States of America

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• William R. Lagor,

  Roles Funding acquisition

  Affiliation Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States of America

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• Jason D. Heaney,

  Roles Funding acquisition

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Yujia A. Chan,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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•  [ ... ],
• Benjamin E. Deverman

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bdeverma@broadinstitute.org

  Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0002-6223-9303

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