DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models

• Hao Liu ,

  Contributed equally to this work with: Hao Liu, René N. Caballero-Florán, Ty Hergenreder

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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• René N. Caballero-Florán ,

  Contributed equally to this work with: Hao Liu, René N. Caballero-Florán, Ty Hergenreder

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Ty Hergenreder ,

  Contributed equally to this work with: Hao Liu, René N. Caballero-Florán, Ty Hergenreder

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

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• Tao Yang,

  Roles Investigation, Methodology

  Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

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• Jacob M. Hull,

  Roles Methodology

  Affiliation Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Geng Pan,

  Roles Formal analysis

  Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

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• Ruonan Li,

  Roles Methodology, Writing – review & editing

  Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

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• Macy W. Veling,

  Roles Methodology

  Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America

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• Lori L. Isom,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Kenneth Y. Kwan,

  Roles Resources, Writing – review & editing

  Affiliations Michigan Neuroscience Institute, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Z. Josh Huang,

  Roles Resources, Writing – review & editing

  Affiliations Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Biomedical Engineering, Duke University Pratt School of Engineering, Durham, North Carolina, United States of America

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• Peter G. Fuerst,

  Roles Resources

  Affiliation University of Idaho, Department of Biological Sciences, Moscow, Idaho, United States of America

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• Paul M. Jenkins ,

  Roles Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: pjenkins@umich.edu (PMJ); bingye@umich.edu (BY)

  Affiliations Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Bing Ye

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: pjenkins@umich.edu (PMJ); bingye@umich.edu (BY)

  ¶‡ Lead contact.

  Affiliations Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-8828-4065

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