A D-2-hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development

• Olga Ponomarova,

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Hefei Zhang,

  Roles Investigation

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Xuhang Li,

  Roles Investigation

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Shivani Nanda,

  Roles Investigation

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Thomas B. Leland,

  Roles Investigation

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Bennett W. Fox,

  Roles Investigation

  Affiliation Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America

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• Alyxandra N. Starbard,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Gabrielle E. Giese,

  Roles Investigation

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Frank C. Schroeder,

  Roles Supervision

  Affiliation Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America

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• L. Safak Yilmaz,

  Roles Investigation, Supervision

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

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• Albertha J. M. Walhout

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: marian.walhout@umassmed.edu

  Affiliation Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America

  https://orcid.org/0000-0001-5587-3608

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