The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems

Charlotte Decourt; Julia Schaeffer; Beatrice Blot; Antoine Paccard; Blandine Excoffier; Mario Pende; Homaira Nawabi; Stephane Belin

doi:10.1371/journal.pbio.3002044

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Peer-reviewed

Research Article

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems

Charlotte Decourt,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
⨯
Julia Schaeffer,

Roles Data curation, Investigation

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
⨯
Beatrice Blot,

Roles Investigation

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
⨯
Antoine Paccard,

Roles Investigation

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
⨯
Blandine Excoffier,

Roles Investigation

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
⨯
Mario Pende,

Roles Methodology, Resources

Affiliation Institut Necker Enfants Malades, INSERM U1151, Université de Paris, Paris, France
⨯
Homaira Nawabi,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
⨯
Stephane Belin

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: stephane.belin@inserm.fr

Affiliation Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France

https://orcid.org/0000-0001-7074-6885

⨯

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems

Charlotte Decourt,
Julia Schaeffer,
Beatrice Blot,
Antoine Paccard,
Blandine Excoffier,
Mario Pende,
Homaira Nawabi,
Stephane Belin

Published: April 17, 2023
https://doi.org/10.1371/journal.pbio.3002044

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Nerve regeneration
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Neurons
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Axons
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Sciatic nerves
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Neurites
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Regeneration
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Scanning electron microscopy
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