Early transcriptional and epigenetic divergence of CD8⁺ T cells responding to acute versus chronic infection

• Lauren K. Quezada ,

  Contributed equally to this work with: Lauren K. Quezada, Wenhao Jin

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Wenhao Jin ,

  Contributed equally to this work with: Lauren K. Quezada, Wenhao Jin

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Yi Chia Liu,

  Roles Investigation

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Eleanor S. Kim,

  Roles Investigation

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Zhaoren He,

  Roles Data curation, Formal analysis

  Affiliation Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Cynthia S. Indralingam,

  Roles Investigation

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Tiffani Tysl,

  Roles Investigation

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Lara Labarta-Bajo,

  Roles Investigation

  Affiliation Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Ellen J. Wehrens,

  Roles Investigation

  Affiliation Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Yeara Jo,

  Roles Investigation

  Affiliation Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Katelynn R. Kazane,

  Roles Investigation

  Affiliation Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Christopher Hattori,

  Roles Investigation

  Affiliation Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Elina I. Zuniga,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Gene W. Yeo,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America, Institute for Genomic Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• John T. Chang

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: changj@ucsd.edu

  Affiliations Department of Medicine, University of California San Diego, La Jolla, California, United States of America, Department of Medicine, Jennifer Moreno Department of Veteran Affairs Medical Center, San Diego, California, United States of America

  https://orcid.org/0000-0003-0873-6218

  ⨯