Identification of genetic variants of the industrial yeast Komagataella phaffii (Pichia pastoris) that contribute to increased yields of secreted heterologous proteins

• Benjamin Offei,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland

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• Stephanie Braun-Galleani,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland, School of Biochemical Engineering, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

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• Anjan Venkatesh,

  Roles Investigation

  Affiliation UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland

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• William T. Casey,

  Roles Investigation

  Affiliation Bioplastech Ltd., NovaUCD, Belfield Innovation Park, University College Dublin, Dublin, Ireland

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• Kevin E. O’Connor,

  Roles Investigation

  Affiliations UCD Earth Institute and School of Biomolecular & Biomedical Science, University College Dublin, Dublin, Ireland, BiOrbic Bioeconomy SFI Research Centre, University College Dublin, Dublin, Ireland

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• Kevin P. Byrne,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliation UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland

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• Kenneth H. Wolfe

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: kenneth.wolfe@ucd.ie

  Affiliation UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland

  https://orcid.org/0000-0003-4992-4979

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